Dual-sided centripetal microgrooved poly (D,L-lactide-co-caprolactone) disk encased in immune-regulating hydrogels for enhanced bone regeneration
Well-designed artificial scaffolds are urgently needed due to the limited self-repair capacity of bone, which hampers effective regeneration in critical defects.Optimal scaffolds must provide physical guidance to Medical and Ambulatory supplies / Wound Care recruit cells and immune regulation to improve the regenerative microenvironment.This study